Timing chromosomal abnormalities using mutation data
نویسندگان
چکیده
منابع مشابه
Methods and challenges in timing chromosomal abnormalities within cancer samples
MOTIVATION Tumors acquire many chromosomal amplifications, and those acquired early in the lifespan of the tumor may be not only important for tumor growth but also can be used for diagnostic purposes. Many methods infer the order of the accumulation of abnormalities based on their occurrence in a large cohort of patients. Recently, Durinck et al. (2011) and Greenman et al. (2012) developed met...
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Background & Aims: Chromosome abnormalities are a major cause of miscarriage and neonatal mortality. The present study aimed to determine the association of fetal and parents chromosomal abnormalities with congenital anomalies. Methods: A cross-sectional study was performed in a tertiary referral center (Afzalipour Hospital) over 16 months period (2011-2012). The study groups consisted of 77 fe...
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ژورنال
عنوان ژورنال: Genome Biology
سال: 2011
ISSN: 1465-6906
DOI: 10.1186/gb-2011-12-s1-p39